Matchup Index

Houston Texans vs San Francisco 49ers

Houston Texans 2
San Francisco 49ers leads 4-2
wins
2005 to 2025
Houston Texans won the last meeting
San Francisco 49ers 4

Series timeline

▼ San Francisco 49ers ahead (peak +3)
2005: San Francisco 49ers 20-172009: Houston Texans 24-212013: San Francisco 49ers 34-32017: San Francisco 49ers 26-162021: San Francisco 49ers 23-72025: Houston Texans 26-15

Houston Texans San Francisco 49ers Tie Postseason One meeting per cell

Longest streaks: Houston Texans 1 (2009), San Francisco 49ers 3 (2013–2021). Current: Houston Texans 1.

Splits

SplitHouston Texans record
Regular season2-4
Hosted by Houston Texans2-1
Hosted by San Francisco 49ers0-3
Last 6 seasons (2005 to 2025)2-4
Largest Houston Texans win26-15 (2025)
Largest San Francisco 49ers win34-3 (2013)

Every meeting

2020s
SeasonDateWinnerScoreSiteRound
2025 Oct 26, 2025 Houston Texans 26-15 at Houston Texans Week 8
2021 Jan 2, 2022 San Francisco 49ers 23-7 at San Francisco 49ers Week 17
2010s
SeasonDateWinnerScoreSiteRound
2017 Dec 10, 2017 San Francisco 49ers 26-16 at Houston Texans Week 14
2013 Oct 6, 2013 San Francisco 49ers 34-3 at San Francisco 49ers Week 5
2000s
SeasonDateWinnerScoreSiteRound
2009 Oct 25, 2009 Houston Texans 24-21 at Houston Texans Week 7
2005 Jan 1, 2006 San Francisco 49ers 20-17 at San Francisco 49ers Week 17

Sources

Records are computed from every final game result in the Matchup Index database. About the data.